Zyderm

Experience the Art of Collagen

Introduced in 1981 and 1985 respectively, Zyderm® and Zyplast® collagen implants have set the standard in filler materials for smoothing facial lines, wrinkles and scars and in providing lip border definition. Today, more than 1.5 million people worldwide have been treated with Zyderm or Zyplast collagen implants.

Treatment with Zyderm and Zyplast implants consists of an initial consultation with a physician, a skin test (given four weeks prior to treatment) and a simple in-office procedure that can be completed quickly and conveniently, even during a lunch hour. Most patients return to their normal routine immediately following the procedure.

Zyderm and Zyplast implants remain the most widely used, safe, and effective choices for smoothing lines, wrinkles, scars, and for defining the lip border.

Dermatologists, plastic surgeons and facial plastic surgeons use Zyderm and Zyplast implants in their practices daily.

Although the information will not take the place of a consultation with your doctor, it should answer some of the questions you may have about treatments with Zyderm and Zyplast.

What are Zyderm and Zyplast made of?

Zyderm and Zyplast collagen implants are composed of highly purified bovine (cow) dermal tissue. This material is obtained from the hides of steers within a closed herd.

How long have people been using bovine-based collagen?


Zyderm bovine-based collagen has been used since 1981 and Zyplast since 1985. Over 1.5 million patients have been treated with Zyderm and Zyplast collagen implants worldwide.

Has bovine-based collagen been approved by the Food and Drug Administration (FDA)?


Yes. Zyderm and Zyplast collagen implants, are FDA-approved to treat fine to deep wrinkles, frown lines, smile lines, crow's feet, the lip border, acne and other scars.

Is Zyderm and Zyplast safe?


Yes. They are a highly purified form of bovine collagen, derived from a USDA-certified and carefully monitored closed herd of cattle in California. There has been no case of BSE or any other herd-threatening disease in the closed cattle herd used to source Zyderm and Zyplast.

What is a closed herd?


A closed herd is defined as one in which:
  • there is no case of Bovine Spongiform Encephalopathy (BSE);
  • there is no feeding of mammalian-derived (animal by-products) protein;
  • there is fully documented breeding history;
  • there is fully documented veterinary monitoring;
  • each animal is monitored and traceable; and
  • genetic material has been introduced only from herds with the same BSE-free status.

How is Zyderm and Zyplast injected?


Zyderm and Zyplast collagen is injected through a tiny needle just below the surface of the skin to smooth wrinkles or define the lip border.

How long does a treatment last?


Treatments generally last 3-6 months.

What are the treatment steps?


A skin test must be administered 4 weeks prior to treatment to screen for a preexisting allergy to bovine collagen. 3% of patients have reported allergic reactions to bovine collagen.

Who can inject collagen?


Injections must be performed by a physician or a qualified healthcare professional.

How much does it cost?


Treatment prices are based on the number of areas treated and the amount of product used. Your physician will help you develop a program that suits your needs.
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